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Repairing a human liver using lab-grown cells. Using oral antibiotics to treat cystic fibrosis patients. Producing a single-dose treatment for breast cancer that’s proving highly effective. Predicting cancer with AI. All of this innovation came out of the UK life sciences industry.

Life sciences v3 1

“It’s really the only industry that can both improve the health of your population and, therefore, their productivity,” says George Freeman, the UK’s Minister of State in the Department for Science, Innovation and Technology. Before being elected to Parliament, Freeman had a 15-year career in the life sciences sector. During that time, he worked with hospitals, clinical researchers, patient groups, and biomedical research companies to pioneer novel healthcare innovations.

Issues facing the global community have also spurred innovation in life sciences. Research in areas like agriculture technology and virology could help address some of the challenges wrought by climate change, which, as Freeman asserts, directly contribute to global instability. “The big flashpoints geopolitically in the next few years are probably going to be around water, food, pandemics, energy.”

And the industry has had other measurable results. Turnover in the UK’s life sciences industry jumped from £63.5 billion in 2016 to £94.2 billion in 2021.

Guided by proven expertise and academic excellence

With two of the top five universities for biological sciences in the world — the University of Cambridge and the University of Oxford — the UK has a solid foundation for investment in life science innovation. “We have really deep science that you can’t buy off the shelf,” Freeman says.

As an example, Freeman points to the MRC Laboratory of Molecular Biology, which has 24 Nobel prizes shared among its researchers and alumni in chemistry, and medicine and physiology. In the area of chemistry, the MRC Laboratory has more Nobel prizes than the entire country of France. “Those kinds of labs don’t just suddenly appear; they are incubated through layers of great science over years,” Freeman says.

The UK has also long been home to a strong pharmaceutical industry. For example, GlaxoSmithKline can trace its history in the UK back to 1715 and it now has nine manufacturing sites there. And AstraZeneca, which was formed after a merger between British and Swedish companies in 1999, bases its global headquarters in Cambridge. “We’ve had some big pharmaceutical companies here, and they’ve stayed here,” Freeman comments, pointing to the expertise this alone has incubated in the UK.

The National Health Service leads the way

Another factor that has enabled the UK to emerge as a leader in life sciences R&D is the National Health Service (NHS), one of the world’s first universal healthcare systems. Dr. Julia Wilson, associate director at the Wellcome Sanger Institute, says, “If you’re going to do longitudinal large-scale studies, following patients over time with repeated monitoring of diseases, risk factors or health outcomes, then you need a healthcare system that can enable you to access all the relevant information and recall patients.”

Such studies undertaken by the NHS have focused on issues like long covid and cognition in people over 50 years of age. “These studies are very much a partnership with the patient, scientists, and clinicians,” says Wilson. However, the institutions supporting life sciences R&D in the UK do not co-exist in a vacuum. There is “a good track record of collaboration across the different sectors,” Wilson says. “Within life sciences, there is porosity between academia, commercial, NHS, that really helps our R&D succeed and deliver.”

Deliberate collaboration for cutting-edge research

This collaboration is backed up by investment from both the government, as well as the charity sector. One such charitable global health foundation, the Wellcome Trust, announced in early 2022 that it would invest £16 billion in the UK over the next 10 years in four interlinked areas of life sciences: discovery research, infectious disease, mental health, and climate and health.

Although the UK excels in innovation for infectious diseases, immunology, and ageing, it is also a powerhouse in the area of genomics. The country’s

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By: MIT Technology Review Insights
Title: Investing in life sciences R&D by design
Sourced From: www.technologyreview.com/2023/03/23/1070030/investing-in-life-sciences-rd-by-design/
Published Date: Thu, 23 Mar 2023 15:28:13 +0000

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The Download: artificial surf pools, and unfunny AI

This is today’s edition of The Download our weekday newsletter that provides a daily dose of what’s going on in the world of technology.

The cost of building the perfect wave

For nearly as long as surfing has existed, surfers have been obsessed with the search for the perfect wave.

While this hunt has taken surfers from tropical coastlines to icebergs, these days that search may take place closer to home. That is, at least, the vision presented by developers and boosters in the growing industry of surf pools, spurred by advances in wave-­generating technology that have finally created artificial waves surfers actually want to ride.

But there’s a problem: some of these pools are in drought-ridden areas, and face fierce local opposition. At the core of these fights is a question that’s also at the heart of the sport: What is the cost of finding, or now creating, the perfect wave—and who will have to bear it? Read the full story.

—Eileen Guo

This story is from the forthcoming print issue of MIT Technology Review, which explores the theme of Play. It’s set to go live on Wednesday June 26, so if you don’t already, subscribe now to get a copy when it lands.

What happened when 20 comedians got AI to write their routines

AI is good at lots of things: spotting patterns in data, creating fantastical images, and condensing thousands of words into just a few paragraphs. But can it be a useful tool for writing comedy?

New research from Google DeepMind suggests that it can, but only to a very limited extent. It’s an intriguing finding that hints at the ways AI can—and cannot—assist with creative endeavors more generally. Read the full story.

—Rhiannon Williams

The must-reads

I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.

1 Meta has paused plans to train AI on European user data
Data regulators rebuffed its claims it had “legitimate interests” in doing so. (Ars Technica)
Meta claims it sent more than two billion warning notifications. (TechCrunch)
How to opt out of Meta’s AI training. (MIT Technology Review)

2 AI assistants and chatbots can’t say who won the 2020 US election
And that’s a major problem as we get closer to the 2024 polls opening. (WP $)
Online conspiracy theorists are targeting political abuse researchers. (The Atlantic $)
Asking Meta AI how to disable it triggers some interesting conversations. (Insider $)
Meta says AI-generated election content is not happening at a “systemic level.” (MIT Technology Review)

3 A smartphone battery maker claims to have made a breakthrough
Japanese firm TDK says its new material could revolutionize its solid-state batteries. (FT $)
And it’s not just phones that could stand to benefit. (CNBC)
Meet the new batteries unlocking cheaper electric vehicles. (MIT Technology Review)

4 What should AI logos look like?
Simple, abstract and non-threatening, if these are anything to go by. (TechCrunch)

5 Radiopharmaceuticals fight cancer with molecular precision
Their accuracy can lead to fewer side effects for patients. (Knowable Magazine)

6 UK rail passengers’ emotions were assessed by AI cameras 
Major stations tested surveillance cameras designed to predict travelers’ emotions. (Wired $)
The movement to limit face recognition tech might finally get a win. (MIT Technology Review)

7 The James Webb Space Telescope has spotted dozens of new supernovae
Dating back to the early universe. (New Scientist $)

8 Rice farming in Vietnam has had a hi-tech makeover
Drones and AI systems are making the laborious work a bit simpler. (Hakai Magazine)
How one vineyard is using AI to improve its winemaking. (MIT Technology Review)

9 Meet the researchers working to cool down city parks
Using water misters, cool tubes, and other novel techniques. (Bloomberg $)
Here’s how much heat your body can take. (MIT Technology Review)

10 The latest generative AI viral trend? Pregnant male celebrities.
The stupider and weirder the image, the better. (Insider $)

Quote of the day

“It’s really easy to get people addicted to things like social media or mobile games. Learning is really hard.”

—Liz Nagler, senior director of product management at language app Duolingo, tells the Wall Street Journal it’s far trickier to get people to go back to the app every day than you might think.

The big story

The big new idea for making self-driving cars that can go anywhere

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May 2022

When Alex

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By: Rhiannon Williams
Title: The Download: artificial surf pools, and unfunny AI
Sourced From: www.technologyreview.com/2024/06/17/1093925/the-download-artificial-surf-pools-and-unfunny-ai/
Published Date: Mon, 17 Jun 2024 12:10:00 +0000

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These board games want you to beat climate change

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It’s game night,and I’m crossing my fingers, hoping for a hurricane.

I roll the die and it clatters across the board, tumbling to a stop to reveal a tiny icon of a tree stump. Bad news: I just triggered deforestation in the Amazon. That seals it. I failed to stop climate change—at least this board-game representation of it.

The urgent need to address climate change might seem like unlikely fodder for a fun evening. But a growing number of games are attempting to take on the topic, including a version of the bestseller Catan released this summer.

As a climate reporter, I was curious about whether games could, even abstractly, represent the challenge of the climate crisis. Perhaps more crucially, could they possibly be any fun?

My investigation started with Daybreak, a board game released in late 2023 by a team that includes the creator of Pandemic (infectious disease—another famously light topic for a game). Daybreak is a cooperative game where players work together to cut emissions and survive disasters. The group either wins or loses as a whole.

When I opened the box, it was immediately clear that this wouldn’t be for the faint of heart. There are hundreds of tiny cardboard and wooden pieces, three different card decks, and a surprisingly thick rule book. Setting it up, learning the rules, and playing for the first time took over two hours.

the components of the game Daybreak which has Game cards depicting Special Drawing Rights, Clean Electricity Plants, and Reforestation themed play cards
Daybreak, a cooperative board game about stopping climate change.COURTESY OF CMYK

Daybreak is full of details, and I was struck by how many of them it gets right. Not only are there cards representing everything from walkable cities to methane removal, but each features a QR code players can use to learn more.

In each turn, players deploy technologies or enact policies to cut climate pollution. Just as in real life, emissions have negative effects. Winning requires slashing emissions to net zero (the point where whatever’s emitted can be soaked up by forests, oceans, or direct air capture). But there are multiple ways for the whole group to lose, including letting the global average temperature increase by 2 °C or simply running out of turns.

In an embarrassing turn of events for someone who spends most of her waking hours thinking about climate change, nearly every round of Daybreak I played ended in failure. Adding insult to injury, I’m not entirely sure that I was having fun. Sure, the abstract puzzle was engaging and challenging, and after a loss, I’d be checking the clock, seeing if there was time to play again. But once all the pieces were back in the box, I went to bed obsessing about heat waves and fossil-fuel disinformation. The game was perhaps representing climate change a little bit too well.

I wondered if a new edition of a classic would fare better. Catan, formerly Settlers of Catan, and its related games have sold over 45 million copies worldwide since the original’s release in 1995. The game’s object is to build roads and settlements, setting up a civilization.

In late 2023, Catan Studios announced that it would be releasing a version of its game called New Energies, focused on climate change. The new edition, out this summer, preserves the same central premise as the original. But this time, players will also construct power plants, generating energy with either fossil fuels or renewables. Fossil fuels are cheaper and allow for quicker expansion, but they lead to pollution, which can harm players’ societies and even end the game early.

Before I got my hands on the game, I spoke with one of its creators, Benjamin Teuber, who developed the game with his late father, Klaus Teuber, the mastermind behind the original Catan.

To Teuber, climate change is a more natural fit for a game than one might expect. “We believe that a good game is always around a dilemma,” he told me. The key is to simplify the problem sufficiently, a challenge that took the team dozens of iterations while developing New Energies. But he also thinks there’s a need to be at least somewhat encouraging. “While we have a severe topic, or maybe even especially because we have a severe topic, you can’t scare off the

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By: Casey Crownhart
Title: These board games want you to beat climate change
Sourced From: www.technologyreview.com/2024/06/14/1093384/catan-climate-change-board-games/
Published Date: Fri, 14 Jun 2024 09:00:00 +0000

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https://mansbrand.com/the-download-milk-beyond-cows-and-geoengineerings-funding-boom/

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The Download: milk beyond cows, and geoengineering’s funding boom

This is today’s edition of The Download our weekday newsletter that provides a daily dose of what’s going on in the world of technology.

Biotech companies are trying to make milk without cows

The outbreak of avian influenza on US dairy farms has started to make milk seem a lot less wholesome. Milk that’s raw, or unpasteurized, can actually infect mice that drink it, and a few dairy workers have already caught the bug.

The FDA says that commercial milk is safe because it is pasteurized, killing the germs. Even so, it’s enough to make a person ponder a life beyond milk—say, taking your coffee black or maybe drinking oat milk.

But for those of us who can’t do without the real thing, it turns out some genetic engineers are working on ways to keep the milk and get rid of the cows instead. Here’s how they’re doing it.

—Antonio Regalado

This story is from The Checkup, our weekly biotech and health newsletter. Sign up to receive it in your inbox every Thursday.

This London non-profit is now one of the biggest backers of geoengineering research

A London-based nonprofit is poised to become one of the world’s largest financial backers of solar geoengineering research. It’s just one of a growing number of foundations eager to support scientists exploring whether the world could ease climate change by reflecting away more sunlight.

The uptick in funding will offer scientists in the controversial field far more support than they’ve enjoyed in the past. This will allow them to pursue a wider array of lab work, modeling, and potentially even outdoor experiments that could improve our understanding of the benefits and risks of such interventions. Read the full story.

—James Temple

How to opt out of Meta’s AI training

If you post or interact with chatbots on Facebook, Instagram, Threads, or WhatsApp, Meta can use your data to train its generative AI models beginning June 26, according to its recently updated privacy policy.

Internet data scraping is one of the biggest fights in AI right now. Tech companies argue that anything on the public internet is fair game, but they are facing a barrage of lawsuits over their data practices and copyright. It will likely take years until clear rules are in place.

In the meantime, if you’re uncomfortable with having Meta use your personal information and intellectual property to train its AI models, consider opting out. Here’s how to do it.

—Melissa Heikkila

The must-reads

I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.

1 The US Supreme Court has upheld access to the abortion pill
It’s the most significant ruling since it overturned Roe v Wade in 2022. (FT $)
The decision represents the aversion of a major crisis for reproductive health. (Wired $)
But states like Kansas are likely to draw out legal arguments over access. (The Guardian)

2 Amazon is struggling to revamp Alexa
It’s repeatedly missed deadlines and is floundering to catch up with its rivals. (Fortune)
OpenAI has stolen a march on Amazon’s AI assistant ambitions. (MIT Technology Review)

3 Clearview AI has struck a deal to end a privacy class action
If your face was scraped as facial recognition data, you may be entitled to a stake in the company. (NYT $)
The startup doesn’t have the funds to settle the lawsuit. (Reuters)
It was fined millions of dollars for its practices back in 2022. (MIT Technology Review)

4 What’s next for nanotechnology
Molecular machines to kill bacteria aren’t new—but they are promising. (New Yorker $)

5 The Pope is a surprisingly influential voice in the AI safety debate
Pope Francis will address G7 leaders who have gathered today to discuss AI regulation. (WP $)
Smaller startups are lobbying to be acquired by bigger fish. (Bloomberg $)
What’s next for AI regulation in 2024? (MIT Technology Review)

6 Keeping data centers cool uses colossal amounts of power
Dunking servers in oil could be a far more environmentally-friendly method. (IEEE Spectrum)

7 UK voters can back an AI-generated candidate in next month’s election
How very Black Mirror. (NBC News)

8 How to tell if your boss is spying on you
Checking your browser extensions is a good place to start. (WP $)

9We don’t know much about how the human body reacts to space
But with the rise of space tourism, scientists are hoping to find out. (TechCrunch)
This startup wants to find out if humans can have babies in space. (MIT Technology Review)

10 This platform is a who’s-who of rising internet stars
Famous Birthdays is basically a directory of hugely successful teenagers you’ve never heard of. (Economist $)

Quote of the day

“If it’s somebody on the right, I reward them. If it’s somebody

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By: Rhiannon Williams
Title: The Download: milk beyond cows, and geoengineering’s funding boom
Sourced From: www.technologyreview.com/2024/06/14/1093797/the-download-milk-beyond-cows-and-geoengineerings-funding-boom/
Published Date: Fri, 14 Jun 2024 12:10:00 +0000

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