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In America, at least 17 people a day die waiting for an organ transplant. But instead of waiting for a donor to die, what if we could someday grow our own organs?

Last week, six years after NASA announced its Vascular Tissue Challenge, a competition designed to accelerate research that could someday lead to artificial organs, the agency named two winning teams. The challenge required teams to create thick, vascularized human organ tissue that could survive for 30 days. 

The two teams, named Winston and WFIRM, both from the Wake Forest Institute for Regenerative Medicine, used different 3D-printing techniques to create lab-grown liver tissue that would satisfy all of NASA’s requirements and maintain their function.

“We did take two different approaches because when you look at tissues and vascularity, you look at the body doing two main things,” says Anthony Atala, team leader for WFIRM and director of the institute. 

The two approaches differ in the way vascularization—how blood vessels form inside the body—is achieved. One used tubular structures and the other spongy tissue structures to help deliver cell nutrients and remove waste. According to Atala, the challenge represented a hallmark for bioengineering because the liver, the largest internal organ in the body, is one of the most complex tissues to replicate due to the high number of functions it performs.

Liver tissue created by team Winston for NASA’s Vascular Tissue Challenge.WAKE FOREST INSTITUTE FOR REGENERATIVE MEDICINE

“When the competition came out six years ago, we knew we had been trying to solve this problem on our own,” says Atala.

Along with advancing the field of regenerative medicine and making it easier to create artificial organs for humans who need transplants, the project could someday help astronauts on future deep-space missions.

The concept of tissue engineering has been around for more than 20 years, says Laura Niklason, a professor of anesthesia and biomedical engineering at Yale, but the growing interest in space-based experimentation is starting to transform the field. “Especially as the world is now looking at private and commercial space travel, the biological impacts of low gravity are going to become more and more important, and this is a great tool for helping to understand that.”

But the winning teams must still overcome one of the biggest hurdles in tissue engineering: “Getting things to survive and maintain their function over an extended period is really challenging,” says Andrea O’Connor, head of biomedical engineering at the University of Melbourne, who calls this project, and others like it ambitious.

Equipped with a $300,000 cash prize, the first-place team—Winston—will soon have a chance to send its research to the International Space Station, where similar organ research has already taken place.

In 2019, astronaut Christina Koch activated the BioFabrication Facility (BFF), which was created by the Greenville, Indiana-based aerospace research company Techshot to print organic tissues in microgravity.

That research project has goals similar to those of NASA’s Vascular Tissue Challenge, says Eugene Boland, Techshot’s chief scientist. Except instead of 3D-printing liver tissue, their aim is to create transplantable cardiac tissue sometime in the next 10 years. 

What’s different about printing organs and tissues on Earth versus doing it in space? Boland described the difference in techniques by likening the mechanics of printing with Play-Doh to printing with honey.

This year, the BFF is due for an upgrade—one that Rich Boling, vice president of corporate advancement for Techshot, says may make the potentially life-saving technology better suited for future commercialization both in space and back on Earth. In the next few months, that upgrade will involve adding the capability to print with blunt needles—the same kind used to print back on the ground.

“This has always been, for the most part, of the Earth, for the Earth. We’ve always felt like we’re doing this for things like the, for example, organ donor shortage,” Boling said.

Techshot also envisions someday using artificial tissue and organs to help treat diseases, and even congenital defects.

And artificial organs and human tissues are only two of many resources that may be in demand on future space missions. Soon, Techshot plans to enter NASA’s Deep

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By: Tatyana Woodall
Title: NASA inches closer to printing artificial organs in space
Sourced From: www.technologyreview.com/2021/06/18/1026556/nasa-bioprinting-artificial-organs-space/
Published Date: Fri, 18 Jun 2021 12:00:00 +0000

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LATAM crypto exchange Bitso and FMF launch NFT of Mexico’s National Team jerseys

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Bitso, a leading cryptocurrency platform operating in Latin America, and the Mexican Football Federation (FMF), today announced the joint launch of the first collectible NFT of the Mexico National Team’s jerseys that was acquired in cryptocurrencies.

This morning through their social media platforms, the FMF and Bitso announced the opportunity to acquire the new official National Team fan jerseys ahead of the team’s participation in the 2022 World Cup. In just 20 minutes, the entire collection sold out.

bitsonftjeysey
The NFTs of the jerseys have an exclusive design for the metaverse – each is unique on the blockchain and can be resold by its owner in subsequent transactions.

The collection consisted of 100 official physical jerseys, each with a corresponding NFT version of the jersey that fans’ avatars can wear within the Decentraland metaverse. Each physical and NFT jersey set sold for the equivalent of $1,800 MXN in ethers.

“Our mission is to make cryptocurrency useful in the everyday life of Mexicans; we are committed to spreading the technology through innovative opportunities that help people throughout the country familiarize themselves with this new world. We are very excited to offer the incredible, historic opportunity for the fans of our National Team so that through their Bitso account, they can wear the colors of the National Team on and ‘off’ the field in the metaverse.”
– Bárbara González Briseño, General Director of Bitso México

Jersey NFTs

Created by Bitso, the virtual jersey sports the official colors of Mexico and the new National Team shield, characteristics that will make it stand out when users wear it in the virtual world of Decentraland.

The post LATAM crypto exchange Bitso and FMF launch NFT of Mexico’s National Team jerseys appeared first on CryptoNinjas.

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By: CryptoNinjas.net
Title: LATAM crypto exchange Bitso and FMF launch NFT of Mexico’s National Team jerseys
Sourced From: www.cryptoninjas.net/2022/07/29/latam-crypto-exchange-bitso-and-fmf-launch-nft-of-mexicos-national-team-jerseys/
Published Date: Fri, 29 Jul 2022 15:19:02 +0000

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Long-running crypto exchange EXMO unveils “lively” rebrand amidst growth

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EXMO, a crypto exchange platform operating since 2014, announced this week a rebranded visual identity with includes a new logo, brand colors, and design features. This new branding comes as EXMO continues to grow its crypto platform while also seeking to expand its presence in other jurisdictions.

Some new developments underway at EXMO:

Soon, users will be able to earn passive income from EXMO’s new staking platform.Plans to launch an EXMO crypto debit card.Expansion of its services in international markets with the opening of offices in Poland and Lithuania.

EXMO’s new logo

The rationale for the re-brand:

“At EXMO, we have a vision of a world where crypto is in every wallet. Hassle-free. We want to achieve this by making crypto as simple and accessible to everyone as possible. And we know that you already appreciate EXMO for offering user-friendly services and helpful support. Also for the opportunity to trade anywhere and anytime, closing deals in just a few taps. Such important changes required a rethinking of our corporate style, which has long needed a massive upgrade. So today we are introducing a new brand identity for EXMO with a completely new visual concept. We are launching a new logo, brand colors, and design elements. Our key design principles are simplicity, boldness, and a pinch of fun. But most importantly, we have changed our logo. Simple and easily recognizable, it represents the humanity of our brand. The logo stands out due to the wavy letter ‘m’ which symbolizes exchange rate charts and also resembles a spring that will launch you into the crypto world.”
– The EXMO Team regarding the re-branding

The post Long-running crypto exchange EXMO unveils “lively” rebrand amidst growth appeared first on CryptoNinjas.

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By: CryptoNinjas.net
Title: Long-running crypto exchange EXMO unveils “lively” rebrand amidst growth
Sourced From: www.cryptoninjas.net/2022/07/26/long-running-crypto-exchange-exmo-unveils-lively-rebrand-amidst-growth/
Published Date: Tue, 26 Jul 2022 08:10:38 +0000

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Stitching together the grid will save lives as extreme weather worsens

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The blistering heat waves that set temperature records across much of the US in recent days have strained electricity systems, threatening to knock out power in vulnerable regions of the country. 

The electricity has largely stayed online so far this summer, but there have been scattered problems and close calls already. 

Heavy use of energy-sucking air-conditioners is the biggest problem. But intense heat can also reduce the output of power plants, blow transformers, and force power lines to sag. Severe droughts across large parts of the country have also significantly reduced the availability of hydroelectric power, according to the North American Electric Reliability Corporation (NERC). 

It’s unlikely to get better soon. A number of grid operators may struggle to meet peak summer demand, creating the risk of rolling blackouts, the NERC report notes.

The nation’s isolated and antiquated grids are in desperate need of upgrades to keep the lights, heat, and air-conditioning on in the midst of extreme weather events that climate change is making more common, severe, and dangerous. One clear way to ease many of these issues is to more tightly integrate the country’s regional grids, stitching them together with more long-range transmission lines. 

If electricity generated in one area can be more easily shared across much wider regions, power can simply flow to where it’s needed at those moments when customers crank up air-conditioners en masse, or when power plants or fuel supply lines fail amid soaring temperatures, wildfires, hurricanes, or other events, says Liza Reed, a research manager focused on transmission at the Niskanen Center, a Washington, DC, think tank.  

The problem is it’s proved difficult to build more long-range transmission and grid interconnections for a variety of reasons, including the permitting challenges of erecting wires through private and public lands across cities, counties, and states and the reluctance of local authorities to forfeit control or submit to greater federal oversight.

The case of Texas

The unreliability of the US grid is not a new problem. Severe heat and winter storms have repeatedly exposed the frailty of electricity systems in recent years, leaving thousands to millions of people without power as temperatures spiked or plunged.

One of the fundamental challenges is that the grids today are highly fragmented. There are three main electricity networks within the US: the Eastern Grid, the Western Grid, and the Electric Reliability Council of Texas (ERCOT). But there are numerous regional transmission organizations within those first two systems, including the California Independent System Operator, Southwest Power Pool, PJM Interconnection, New York ISO, and more. 

These grids form a complex web of networks operating under different regulators, rules and market structures, and often with limited connections between them.

Map USA grid
A variety of regional transmission organizations oversee different parts of the nation’s aging and fragmented grids, which operate under different rules and with often limited connections between them.
legend

ERCOT is especially isolated, in part because of the desire among local politicians, citizens, and power companies to avoid added competition, the hassle of following other states’ rules, and oversight from the Federal Energy Regulatory Commission (FERC). But the state offers a case study in why that can be a serious problem amid increasingly harsh climate conditions, Reed says.

The Texas grid operator pleaded with customers several times earlier this month to cut electricity use as blistering summer temperatures created  demand surges that threatened to outstrip supply and require rolling blackouts.  Low wind conditions, cloud cover, and outages at fossil-fuel power plants added to the strains.

Shutting off the electricity needed to run air-conditioning in triple-digit temperatures

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By: James Temple
Title: Stitching together the grid will save lives as extreme weather worsens
Sourced From: www.technologyreview.com/2022/07/28/1056483/stitching-together-the-grid-will-save-lives-as-extreme-weather-worsens/
Published Date: Thu, 28 Jul 2022 08:00:00 +0000

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