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Topical dutasteride is a new solution for hair loss, particularly in males. Find out how it works and its efficacy in promoting hair growth here.

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Hair loss among men is an issue that resonates deeply across various cultures and ages. About 50 percent of men by the age of 50 will experience some degree of androgenetic alopecia–known as male pattern baldness.

This condition not only affects a man’s physical appearance but often comes with significant emotional distress. This issue highlights its urgency and prevalence, emphasizing the continuous search for more effective and user-friendly treatments.

Amidst this ongoing battle against hair loss, a new contender has emerged on the horizon: topical dutasteride. This innovative approach promises to revolutionize men’s hair care with a potent, targeted therapy that mitigates the limitations of previous treatments.

Understanding Hair Loss in Men

Before delving into the specifics of topical dutasteride, it’s best to understand the typical causes of hair loss in men. This condition, which affects a significant portion of the male population, is primarily driven by dihydrotestosterone (DHT), a derivative of testosterone. DHT results in hair loss by shortening the growth phase of hair follicles. This eventually leads to their shrinkage and the cessation of hair production.

Current Treatments and Their Limitations

The therapeutic landscape for hair loss, particularly androgenetic alopecia, has been historically characterized by a scarcity of FDA-approved options. Minoxidil and finasteride are the primary treatments sanctioned for this condition.

Minoxidil, a topical agent, dilates blood vessels and facilitates the opening of potassium channels. This mechanism promotes an enhanced flow of blood, oxygen, and other nutrients to the follicles responsible for supporting growth. However, its mechanism does not directly combat DHT, the androgen hormone primarily implicated in the pathogenesis of hair loss.

On the other hand, finasteride operates through a distinct mechanism. It is an oral inhibitor of the 5-alpha reductase enzyme, pivotal in converting testosterone to DHT. Finasteride directly tackles the hormonal root of hair loss by diminishing DHT levels. Although clinically effective, the use of finasteride has drawbacks. It has adverse effects, including sexual dysfunction and psychological impacts such as depression. These side effects have led to reservations and reluctance among potential users.

These treatments, while foundational in managing hair loss, underscore a critical need for alternative therapies that can offer robust efficacy with a reduced burden of side effects. This gap in treatment efficacy and tolerability catalyzes the ongoing exploration and development of novel interventions, such as topical dutasteride.

The Advancement of Topical Dutasteride

Dutasteride, like finasteride, is a DHT blocker. However, it is more potent as it inhibits both types of the enzyme 5-alpha reductase responsible for converting testosterone to DHT. Initially available as an oral treatment for prostate enlargement, the focus has shifted toward its use in treating scalp hair loss.

Topical dutasteride presents a significant advancement because it minimizes systemic absorption, reducing the risk of side effects associated with oral dutasteride.

Benefits Over Traditional Treatments

Topical dutasteride offers several advantages that make it a compelling option for hair loss treatment. The localized application directly targets the scalp, where DHT’s impact on hair follicles is most detrimental. This direct application enhances the drug’s effectiveness in treating hair loss and significantly reduces the risk of systemic side effects.

Furthermore, studies suggest that dutasteride may be more effective than finasteride in promoting hair growth, providing a stronger case for its use in clinical settings.

The Future of Hair Loss Treatments

Introducing topical dutasteride marks a pivotal moment in men’s hair care, aligning with a broader shift toward more targeted and less invasive therapies. As research continues and safety data become available, topical dutasteride could become

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By: MFM
Title: Revolutionising Men’s Hair Care: The Rise of Topical Dutasteride
Sourced From: www.mensfashionmagazine.com/revolutionising-mens-hair-care-the-rise-of-topical-dutasteride?utm_source=rss&utm_medium=rss&utm_campaign=revolutionising-mens-hair-care-the-rise-of-topical-dutasteride
Published Date: Tue, 14 May 2024 17:40:50 +0000

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EXCLUSIVE: Bianca Umali on Winning an International Award and Working With Nora Aunor

One look at Bianca Umali and you know that she is all about Pinoy pride. From flaunting her morena skin to donning Filipino-made pieces, she does not shy away from representing her race and culture. Of course, you can also count on her own craft as part of Filipino excellence. At 2024 Jinseo International Film Festival, the Kapuso star took the honor of the Best Dramatic Performance award for the film Mananambal. In an exclusive interview with MEGA Entertainment, Bianca gives us a lookback on her movie experience, her Best Actress outfit, and her bright future with her next project, Sang’gre

RELATED: Bianca Umali Teaches Us How to Pose and Post on Instagram

Bianca Umali Jinseo Arigato Festival Best Actress Mananambal
Bianca Umali at the Jinseo Arigato Film Festival

A Shared Victory

“It was an overwhelming feeling of mixed emotions. As an actor, this means the world to me,” the actress begins. “While filming, I just dedicated myself to give more than good justice to my role and make the most out of the working experience with Ms. Nora. Bonus na lang na may makapansin at pumuri sa efforts ko.”

Bianca Umali Jinseo Arigato Festival Best Actress Mananambal Nora Aunor
Bianca with National Artist and Best Actress Nora Aunor for Mananambal

Even in her Gen Z status, the actress is already hoping that her win will inspire the next generations who would like to pursue the same craft as hers. “I dedicate this award to the younger generation of actors as well, especially to the aspiring ones who may face obstacles along the way. I want them to know that their dreams are valid, and with passion, perseverance and the right amount of love and respect for yourself and what you do, anything and everything is possible,” she offers.

A Role of a Lifetime

Perhaps it is Bianca’s consistent and persistent willingness to refine her craft that takes her to greater heights, with recognition just a prefix to her grit. For Mananambal in particular, the actress not only had to play the part but actually look and be it.

Sharing her process, she recounts, “I prepared for it mentally by doing my research about what the life and ways of a true mananambal is. Emotionally, I did personal workshops to build the character and study my scenes. Of course, physically, by growing my hair longer and enhancing my morena skin more for the look of the role.”

Bianca Umali Jinseo Arigato Festival Best Actress Mananambal
Stylist John Paul Dizon worked with Bianca for her looks

During the festival, the actress also exerted her effort for her looks. She reveals to MEGA that throughout their Japan trip, it was only her and her stylist, John Paul Dizon, who collaborated with her ensembles. “He was in charge of my clothing and I was in charge of my hair and make-up,” she shares. “In all the years that JP and I have been working together, what we value the most in our team up is collaboration.”

The Next Bianca on Camera

After the Jinseo Arigato Film Festival, Mananambal has yet to make its Filipino cinema debut. “Iniikot pa sa iba’t ibang film festivals internationally. Pero definitely ay magkakaroon kami ng theatrical release dito sa Pilipinas. Hopefully, by the end of this year,” the Kapuso star says.

Sang'gre Encantadia
The actress plays the daughter of Danaya, known as Terra, in the upcoming series, Sang’gre

Hopping from one project to the next, Bianca is also top billing the next Encantadia series Sang’gre. With fans of the past and today surely on their toes for the series, the actress shares the excitement of the audience. “We have been in the process of creation and taping since November last year. It is a project na pinaglalaanan namin ng napakaraming oras at paghahanda para mapaganda. Hindi na rin ako makapaghintay na makita ng mga tao ito.


Photos and Featured Image: BIANCA UMALI (via Instagram)

The post EXCLUSIVE: Bianca Umali on Winning an International Award and Working With Nora Aunor appeared first on MEGA.

———————————–

By: Chlarine Gianan
Title: EXCLUSIVE: Bianca Umali on Winning an International Award and Working With Nora Aunor
Sourced From: mega-onemega.com/exclusive-bianca-umali-on-winning-a-best-actress-award-and-working-with-nora-aunor/?utm_source=rss&utm_medium=rss&utm_campaign=exclusive-bianca-umali-on-winning-a-best-actress-award-and-working-with-nora-aunor
Published Date: Mon, 10 Jun 2024 05:39:01 +0000

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Fashion

EXCLUSIVE: Bianca Umali on Winning a Best Actress Award and Working With Nora Aunor

One look at Bianca Umali and you know that she is all about Pinoy pride. From flaunting her morena skin to donning Filipino-made pieces, she does not shy away from representing her race and culture. Of course, you can also count on her own craft as part of Filipino excellence. At 2024 Jinseo Arigato Awards, the Kapuso star took the honor of the Best Actress award for the film Mananambal. In an exclusive interview with MEGA Entertainment, Bianca gives us a lookback on her movie experience, her Best Actress outfit, and her bright future with her next project, Sang’gre.

RELATED: Bianca Umali Teaches Us How to Pose and Post on Instagram

Bianca Umali Jinseo Arigato Festival Best Actress Mananambal
Bianca Umali at the Jinseo Arigato Film Festival

A Shared Victory

“It was an overwhelming feeling of mixed emotions. As an actor, this means the world to me,” the actress begins. “While filming, I just dedicated myself to give more than good justice to my role and make the most out of the working experience with Ms. Nora. Bonus na lang na may makapansin at pumuri sa efforts ko.”

Bianca Umali Jinseo Arigato Festival Best Actress Mananambal Nora Aunor
Bianca with National Artist and Best Actress Nora Aunor for Mananambal

Even in her Gen Z status, the actress is already hoping that her win will inspire the next generations who would like to pursue the same craft as hers. “I dedicate this award to the younger generation of actors as well, especially to the aspiring ones who may face obstacles along the way. I want them to know that their dreams are valid, and with passion, perseverance and the right amount of love and respect for yourself and what you do, anything and everything is possible,” she offers.

A Role of a Lifetime

Perhaps it is Bianca’s consistent and persistent willingness to refine her craft that takes her to greater heights, with recognition just a prefix to her grit. For Mananambal in particular, the actress not only had to play the part but actually look and be it.

Sharing her process, she recounts, “I prepared for it mentally by doing my research about what the life and ways of a true mananambal is. Emotionally, I did personal workshops to build the character and study my scenes. Of course, physically, by growing my hair longer and enhancing my morena skin more for the look of the role.”

Bianca Umali Jinseo Arigato Festival Best Actress Mananambal
Stylist John Paul Dizon worked with Bianca for her looks

During the festival, the actress also exerted her effort for her looks. She reveals to MEGA that throughout their Japan trip, it was only her and her stylist, John Paul Dizon, who collaborated with her ensembles. “He was in charge of my clothing and I was in charge of my hair and make-up,” she shares. “In all the years that JP and I have been working together, what we value the most in our team up is collaboration.”

The Next Bianca on Camera

After the Jinseo Arigato Film Festival, Mananambal has yet to make its Filipino cinema debut. “Iniikot pa sa iba’t ibang film festivals internationally. Pero definitely ay magkakaroon kami ng theatrical release dito sa Pilipinas. Hopefully, by the end of this year,” the Kapuso star says.

Sang'gre Encantadia
The actress plays the daughter of Danaya, known as Terra, in the upcoming series, Sang’gre

Hopping from one project to the next, Bianca is also top billing the next Encantadia series Sang’gre. With fans of the past and today surely on their toes for the series, the actress shares the excitement of the audience. “We have been in the process of creation and taping since November last year. It is a project na pinaglalaanan namin ng napakaraming oras at paghahanda para mapaganda. Hindi na rin ako makapaghintay na makita ng mga tao ito.


Photos and Featured Image: BIANCA UMALI (via Instagram)

The post EXCLUSIVE: Bianca Umali on Winning a Best Actress Award and Working With Nora Aunor appeared first on MEGA.

———————————–

By: Chlarine Gianan
Title: EXCLUSIVE: Bianca Umali on Winning a Best Actress Award and Working With Nora Aunor
Sourced From: mega-onemega.com/exclusive-bianca-umali-on-winning-a-best-actress-award-and-working-with-nora-aunor/?utm_source=rss&utm_medium=rss&utm_campaign=exclusive-bianca-umali-on-winning-a-best-actress-award-and-working-with-nora-aunor
Published Date: Mon, 10 Jun 2024 05:39:01 +0000

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Charlie Dizon Ties the Knot With Carlo Aquino After Her First Gawad Urian Win

Charlie Dizon is thriving in life and love as she brings home both an award and a man home with her Best Actress win and her new role as Mrs. Carlo Aquino

Congratulations are definitely in order for Charlie Dizon whose weekend is definitely a double celebration! Last night, the actress won her first Best Actress accolade at the Gawad Urian Awards 2024 for her performance on Third World Romance. But earlier today, she and fellow actor, Carlo Aquino, also finally tied the knot. 

Charlie Dizon Carlo Aquino wedding marriage Silang Cavite Gawad Urian win Third World Romance Steph Tan
Charlie and Carlo tie the knot in an intimate celebration; Photo: MYIO OKAMOTO (via Instagram)

RELATED: EXCLUSIVE: Loisa, Charlie, Elisse, and Alexa Find Their Missing Pieces After Pira-Pirasong Paraiso

In her acceptance speech, Dizon thanked her now-husband whom she called her “partner and lucky charm.” Aquino also starred in the Dwein Baltazar film. The announcement of their wedding surprised many of their fans and supporters, with a number of them still high on Charlie’s victorious moment the night before.

In an Instagram post shared by Star Magic, a number of celebrity guests also attended the wedding. Actors Belle Mariano, Kaila Estrada, Alexa Ilacad, Loisa Andalio, and Elisse Joson, Adrian Lindayag, and Ketchup Eusebio posed with the couple as part of the entourage.

Charlie Dizon Carlo Aquino wedding marriage Silang Cavite Gawad Urian win Third World Romance

Meanwhile, Sue Ramirez also graced the occasion as Charlie’s Maid of Honor, while their principal sponsors include Maricel Soriano, Vilma Santos-Recto, Sylvia Sanchez, Olivia Lamasan, Lauren Dyogi, Carlo Katigbak, Cory Vidanes, and Charo Santos-Concio. “May your marriage be filled with endless love and happiness. Cheers to a wonderful life together!” Santos-Concio wrote in her caption, greeting the couple for their new chapter.

Charlie Dizon Carlo Aquino wedding marriage
Charo Santos at Charlie and Carlo’s wedding; Photo: CHARO SANTOS-CONCIO (via Instagram)

In her back-to-back celebration, the actress sported a sleek bun that showcased her bespoke attires for the respective events. At the 47th Gawad Urian Awards, she wore a baby pink terno with bowed iterations by Jro Alarcio. For her big day in her newest role to date as a wife, she donned an embellished v-neck wedding dress designed by Steph Tan.

Charlie Dizon Carlo Aquino wedding marriage Silang Cavite Gawad Urian win Third World Romance Steph Tan
Charlie wears an ensemble by Steph Tan; Photo: MYIO OKAMOTO (via Instagram)

Featured Image: MYIO OKAMOTO (via Instagram)

The post Charlie Dizon Ties the Knot With Carlo Aquino After Her First Gawad Urian Win appeared first on MEGA.

———————————–

By: Chlarine Gianan
Title: Charlie Dizon Ties the Knot With Carlo Aquino After Her First Gawad Urian Win
Sourced From: mega-onemega.com/charlie-dizon-ties-the-knot-with-carlo-aquino-after-her-first-gawad-urian-win/?utm_source=rss&utm_medium=rss&utm_campaign=charlie-dizon-ties-the-knot-with-carlo-aquino-after-her-first-gawad-urian-win
Published Date: Mon, 10 Jun 2024 01:16:56 +0000

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